Welcome to the homepage for all content related to Rare Variant Association Testing for the GINGER Program! You may navigate to the individual parts within Rare Variant Association Testing by clicking on the tabs below. There are two parts to this module with corresponding videos and learning checks available as you click each link.
Learning Objectives
- Ensembl VEP, LOFTEE, MPC, Alpha Missense, etc
- Defining rare
- Intuition of burden testing
- Differences and pros/cons of various association testing methods such as Fisher’s, Firth, SAIGE-GENE+.
- Visualizing and interpreting results.
Lecture Videos and Learn Checks
Below is an overview of this module. Please watch the required videos and complete the corresponding learning checks to self-assess your comprehension of the key concepts covered. After you have completed the videos and learning checks, please complete the corresponding assignment.