General instructions:
Please complete the following assignment corresponding to Parts 1-3 of Epidemiologic Study Design by no later than Monday, October 12th at 11pm SAST/12am EAT.
At the end of the assignment we ask you to please note 1) approximately how much time you spent on the homework and how much time you spent reviewing the materials (videos and learning checks) , 2) what questions, if any, you have from the videos and/or any places you might have gotten stuck in the assignment, and 3) provide your feedback on the this week’s content and materials. Thank you once again for your assistance in completing these additional questions!
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Question 1 of 20
1. Question
1. A study was designed to understand the association between alcohol consumption and mortality. Participants were males and females aged 18 years and older, living in South Africa, and followed until death (assume there is no other way in which participants leave the study, i.e., there is no loss to follow-up). Recruitment for this study happened between January 1, 2018 and May 1, 2018. On the time axis of ‘time from start of observation’ (or ‘time since study recruitment’), this is an example of:
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Question 2 of 20
2. Question
2. An epidemiologist conducted a prospective cohort study of exercise and stroke, with follow-up from 1975 to 2010. She defined light exercise as exercising, on average, 30 minutes or less per day, moderate exercise as exercising, on average, more than 30 minutes to 1 hour per day, and heavy exercise as exercising, on average, more than 1 hour per day. From 1975 through 1979, subject Q exercised 45 minutes per day. From 1980 through 1989, subject Q exercised 1.5 hours per day. From 1990 through 2004, subject Q exercised 25 minutes per day. Subject Q had a stroke in 2004. Assuming no induction period, how many person-years would subject Q contribute to the moderate exercise exposure group?
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Question 3 of 20
3. Question
Questions 3-5 are adapted from:
Marmot MG, Rose G, Shipley M, and Hamilton PJS. (1976). Employment grade and coronary heart disease in British civil servants. Journal of Epidemiology and Community Health, 32, 244-249. (You do not need to read the full article to answer the questions. Please refer to the text, below, when answering the questions.)
The Whitehall Study was a large cohort study designed to investigate the social determinants of health. The study was established in 1967 by investigators at University College in London and enrolled over 18,000 male British civil servants. Study participants received a physical examination at baseline and were interviewed about their medical history, health behaviors, and professional status. Participants’ employment grade in the British Civil Service was used as a proxy for socioeconomic status. The health outcomes of the civil servants were obtained using the Central Registry of the National Health Service and follow-up over the 7.5-year study period was outstanding (>99%).
3. When evaluating the association between employment grade and death from coronary heart disease (CHD), would you expect the groups with high employment grades and low employment grades to be comparable in terms of other CHD risk factors? Why or why not?
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Question 4 of 20
4. Question
4. Is the Whitehall study a prospective or retrospective study? Open or closed cohort? Explain your reasoning.
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Question 5 of 20
5. Question
5. What measures of association could be directly estimated using this study design?
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Question 6 of 20
6. Question
Questions 6-9 refer to the following article:
Effect of collaborative care between traditional and faith healers and primary health-care workers on psychosis outcomes in Nigeria and Ghana (COSIMPO): a cluster randomised controlled trial. The Lancet, 396(10251), pp.612-622.
Please read the article before answering the questions. You may download the article by clicking here: Collborative care between traditional and faith healers and primary health-care workers on psychosis outcomes in Nigeria and Ghana (COSIMPO)_Gureje
6. How was the randomization conducted? Think of one advantage and one disadvantage of this randomization method.
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Question 7 of 20
7. Question
7. Do you think the randomization was successful? Briefly explain your reasoning.
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Question 8 of 20
8. Question
8. What are the two arms of this RCT?
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Question 9 of 20
9. Question
9. Was this RCT blinded? If so, who were blinded?
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Question 10 of 20
10. Question
How much time did you spend on this homework?
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Question 11 of 20
11. Question
Please include here any questions from the recorded lectures or homework that you would like to be addressed during the lab session.
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Question 12 of 20
12. Question
Your feedback is important to us. So that we can adequately adjust the lecture materials, please answer the questions below relating to each of this week’s topics:
Part 1: Overview of Epidemiological Study Designs
Was the amount of information presented too little, just right, or too much?
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Question 13 of 20
13. Question
The lecture’s contents were clearly explained.
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Question 14 of 20
14. Question
How was the pace of the lecture?
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Question 15 of 20
15. Question
Part 2: RCTs
Was the amount of information presented too little, just right, or too much?
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Question 16 of 20
16. Question
The lecture’s contents were clearly explained.
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Question 17 of 20
17. Question
How was the pace of the lecture?
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Question 18 of 20
18. Question
Part 3: Cohort Study
Was the amount of information presented too little, just right, or too much?
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Question 19 of 20
19. Question
The lecture’s contents were clearly explained.
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Question 20 of 20
20. Question
How was the pace of the lecture?
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